Loyola College B.Sc. Plant Biology and Biotechnology April 2006 Immunology & Immunotechnology Question Paper PDF Download

             LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

B.Sc. DEGREE EXAMINATION – PLANT BIOLOGY & BIOTECHNOLOGY

IB 21

SIXTH SEMESTER – APRIL 2006

                                       PB 6600 – IMMUNOLOGY & IMMUNOTECHNOLOGY

(Also equivalent to PBB 600)

 

 

Date & Time : 26-04-2006/9.00-12.00         Dept. No.                                                       Max. : 100 Marks

 

 

Part A

Answer all the following questions                                                                         (20 marks)

  1. Choose the correct answer (5 x 1 = 5 )

 

  1. Pick out the wrong pair.
  2. a) Yalow-ELISA b) Metchnikoff – phagocytosis
  3. c) Jenner- vaccination d) Kitasato – tetanus toxin.
  4. Which among the following can cross the placenta.
  5. a) IgD b) IgG     c) IgA          d) IgE
  6. Ouchterloy test is associated with .
  7. a) agglutination b) opsonization      c) nertralization       d) precipitation
  8. NK cells refers to _______ cells .
  9. a) neutral killer b) natural killer     c)  native killer         d) naive killer
  10. In hybridoma technology _______ cells are made to fuse with spleen cells.
  11. a) myogenic b) myeloma c) myopia        d) maternal
  12. State whether the following statements are True or False (5 x 1 = 5 )
  13. Pasteur coined the term vaccination .
  14. Haptens are otherwise known as partial antibodies.
  15. Schick test is associated with toxin – antitoxin reactions.
  16. B cells have their origin from bone marrow.
  17. Polyclonal antibodies have many antigenic determinants.

 

III. Complete the following                                                                              (5 x 1 = 5)

  1. ________ _________were first reported by Kohler and Milstein.
  2. _____ are the only antibodies which can cross the placenta
  3. IgM is also called _________.
  4. Wasserman test is used in the diagnosis of ________.
  5. Lymphokines come under ________.
  6. Answer the following in one or two sentences. (5 x 1 = 5)
  7. Mention the contribution of Tonegawa to the field of immunology.
  8. Distinguish between allotype and isotype.
  9. What are the features of Forsmann antigens ?

 

 

 

  1. What are interferons ?
  2. Expand HAT medium.

Part B

 

 Answer any five of the following each in about 350 words.                            (5 x 8 = 40)

  1. Write about the scope of immunology.
  2. Give an outline of immunity.
  3. Write down the characteristics of antigens.
  4. Draw diagrams only of a typical Ig molecule. Why it is said to be bifunctional ?
  5. Bring out the differences between T cells and B cells.
  6. Expand the following with a footnote :
  7. a) BCG b) ARS c)  CFT     d)  HGPRT
  8. Write about the central lymphoid organs.
  9. Discuss the applications of polyclonal antibodies.

Part C

 

Answer the following  questions in about 1500 words. Draw necessary diagrams     (2 x 20 = 40)

  1. a) What are cytokines ?. Mention their properties, types and role in immunity.

OR

  1. Discuss the production of monoclonal antibodies .

 

  1. a) Write about any 2 antigen- antibody reactions.

OR

  1. Write short notes on :
  2. IgE ii. Phagocytosis iii. inflammation

 

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